Stem Cells

Our laboratory is at the forefront of establishing and characterizing novel ESC and iPS cell lines from domestic pig, which are similar to either mouse (naïve) or human (primed) ESC. Our primary goal is to dissect the molecular pathways that establish and sustain these distinct pluripotent states in this model species, and secondarily to improve the overall efficacy of this process. Ultimately, our objective is to utilize the established cells for cellular therapies (Regenerative medicine) and as tools for genetic manipulation and the establishment of live offspring (Transgenics).Stem cells